Study on high incidence of hepatitis C and its epidemiological features in Jianping county, Liaoning Province
10.3760/cma.j.issn.1000-6680.2009.12.009
- VernacularTitle:辽宁省建平县丙型肝炎高发病率及其流行病学特点的初步研究
- Author:
Zongfen LI
;
Yiping FENG
;
Lianzheng YU
;
Li LIU
;
Liya YU
;
Liying XING
;
Lixia HE
;
Guowei PAN
- Publication Type:Journal Article
- Keywords:
Incidences;
Mortality;
Hepatitis C;
Liver cirrhosis;
Carcinoma;
hepatocellular
- From:
Chinese Journal of Infectious Diseases
2009;27(12):746-748
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significantly elevated incidence of hepatitis C and mortality of cirrhosis and hepatocellular carcinoma (HCC) in Jianping county, and to explore the epidemiological features. Methods The data from database of death registry and infectious disease surveillance in Jianping county, Liaoning Province were analyzed. The distributions of incidence of hepatitis B and hepatitis C, mortality of cirrhosis and HCC in 23 villages and towns were investigated.Spearman's correlation was used to explore the correlations between hepatitis, cirrhosis and HCC.Results The standardized mortality of HCC in males and females in Jianping county were 77. 6/10~5and 22. 0/10~5, respectively, which were 2. 0 and 1. 7 times, respectively of the average levels of Liaoning rural areas. The incidence of hepatitis C was 58. 0/10~5 , which was 9. 5 times of the averagelevel of Liaoning Province. There were positive correlations between incidence of hepatitis C and mortality of cirrhosis (r=0. 495, P = 0. 008), and mortality of cirrhosis and HCC (r=0. 646, P<0.01). Conclusions The incidence of hepatitis C and mortality of cirrhosis and HCC in Jianping county are significantly higher than the average levels of Liaoning Province. Further investigations of the suspected causes are needed.
