The cohort study of components of metabolic syndrome related with diabetes mellitus in elderly patients
10.3760/cma.j.issn.0254-9026.2010.01.003
- VernacularTitle:代谢综合征各组分与老年人糖尿病关系的队列研究
- Author:
Ping ZENG
;
Xuefeng ZHU
;
Yi ZHANG
;
Yanli PAN
;
Shu WANG
;
Tiemei ZHANG
- Publication Type:Journal Article
- Keywords:
Metabolic syndrome X;
Diabetes;
type 2;
Cohort study
- From:
Chinese Journal of Geriatrics
2010;29(1):9-12
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation of metabolic syndrome (MS) and its components with a future development of diabetes mellitus (DM) in elderly patients. Methods In 2007, the cohort study was carried out among the 2001 baseline population. The criteria which was proposed by international diabetes federation in 2005 was referred to diagnose MS. Results MS predicted the future development of DM (RR = 4. 70, 95% CI:3.23~6.85). Among MS components, fasting glucose exhibited the highest association with DM. The univariate analysis showed that while fasting glucose was more than 5. 6 mmol/L, the RR(95% CD was 9. 68(6. 59~ 14.23). And multiple factors analysis showed that while fasting glucose was 5.60 mmol/L~6. 09 mmol/L, the RR(95% CD was 5. 49(3. 38~8. 92). While glucose level was more than 6. 1 but less than 7.0 mmol/L, the RR(95% CI) increased to 14.44(9.29~22.44). However, along with the increasing of cluster number of MS components from 1,2,3,4 to 5, the corresponding RR increased from 2. 92, 5. 67, 12. 28, 19. 52 to 37. 83. Conclusions MS increases the risk of DM. Among MS components, fasting glucose level is the strongest risk indicator of DM.