Evaluation of acute kidney injury network criteria in post-cardiosurgery elderly patients with acute kidney injury
10.3760/cma.j.issn.0254-9026.2010.01.007
- VernacularTitle:老年人心血管手术后急性肾功能损伤预后评价的临床观察
- Author:
Xiaolei YAN
;
Xiaotong HOU
;
Yong YANG
;
Ping DONG
;
Ming JIA
;
Jiuhe WAN
;
Shijie JIA
- Publication Type:Journal Article
- Keywords:
Renal insufficiency;
Coronary artery bypass;
Heart Valve prosthesis implantation
- From:
Chinese Journal of Geriatrics
2010;29(1):24-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of acute kidney injury network (AKIN) criteria for predicting hospital mortality in post-cardiosurgery elderly patients. Methods From October 2006 to January 2007, the elderly patients who underwent coronary artery bypass grafting or valve replacement operation were enrolled in this study. The medical data included gender, age, operation type, perioperative hemodynamic parameters, urine output, biochemical parameters and outcome. Renal function was assessed according to the AKIN criteria, and severity of illness was determined after surgery by calculating Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ ) score. Results A total of 225 patients underwent cardiac surgery during this period, 169 patients were male (75. 1%), while 56 were female (24. 9%), mean age was (66. 7±5. 0) years old. The overall hospital mortality rate was 5.8% (13/225). According to AKIN criteria, there were 125 patients with acute kidney injury (55.6%), and the hospital mortality of stage 1, 2 and 3 patients were 2. l%(2/96), 9. 1% (1/11) and 50. 0% (9/18) respectively. A significant increase was observed in mortality based on AKIN criteria (P<0. 01). By applying the area under the receiver operating characteristic curve, the AKIN criteria had a good discriminative power. Conclusions Both the incidence and mortality rate of acute kidney injury in the post-cardiosurgery elderly patients are high, the AKIN criteria is a simple and valuable method with a good prognostic capability for evaluating acute kidney injury.