Effects of glutamine on immune function in elderly patients with malnutrition
10.3760/cma.j.issn.1674-635X.2009.06.007
- VernacularTitle:谷氨酰胺对老年营养不良患者免疫功能的影响
- Author:
Renliang YI
;
Yawen JIANG
- Publication Type:Journal Article
- Keywords:
glutamine;
elderly;
immtme function
- From:
Chinese Journal of Clinical Nutrition
2009;17(6):343-345
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of glutamine on immune function in elderly patients with malnutrition.Methods Twenty-four elderly patients with malnutrition were equally randomized divided into glutamine group and control group.Patients in both two groups were administered with enteral nutrition containing equal nitrogen and calorics for consecutively 7 days.In the glutamine group,patients were also supplied with oral glutamine (7.5g tid).Changes of plasma IgG,IgA,and IgM levels,percentages of T-lymphocyte subsets (CD3,CD4,CD8),and CD4/CD8 ratio were determined before and after treatment.Results Plasma IgG and IgA lev-els,percentages of CD3 and CD4,and CD4/CD8 ratio were significantly higher in glutamine group than in control group (P<0.05 or P<0.01).Conclusion Glutamine can improve the immune function in elderly patients with malnutritiop and promote their recovery.
