Mechanism and targeted therapy of liver metastases of colorectal cancer
10.3760/cma.j.issn.1673-422X.2009.12.021
- VernacularTitle:大肠癌肝转移机制及其靶向治疗
- Author:
Huarong CHEN
;
Weiting GE
;
Shu ZHENG
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Neoplasm metastasis;
Tumor markers;
biological
- From:
Journal of International Oncology
2009;36(12):940-943
- CountryChina
- Language:Chinese
-
Abstract:
The process of liver metastasis of colorectal cancer includes tumor cells invasion,survival in blood stream,extravasation to the liver and proliferation. It is involved in series of molecular markers,among which vascular endothelial growth factor and endothelial growth factor receptor are the major targets.