Relationship between hemoglobin concentration, cytokine and cardiac function in anemic patients with ischemic cardiomyopathy

VernacularTitle:缺血性心肌病患者血红蛋白、细胞因子水平与左室功能的相关性分析
Author: Baoqiao QI ; Jianhua YU ; Xiangjun YANG
Publication Type:Journal Article
Keywords: Cadriomyopathy; ischemic; Hemoglobin concentration; Cytokine; Cardiac function
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(11):1995-1996
CountryChina
Language:Chinese
Abstract: Objective To study the relationships between hemoglobin concentration,cytokine and cardiac function in patients with ischemic cardiomyopathy.Methods Hemoglobin concentration,sernm TNF-α,IL-6 in 121 patients with ischemic cardiomyopathy were measured,left ventricular ejection fraction(LVEF)by echocardiography,according to hemoglobin concentration,these patients were distributed to the anemic group and the non-anemic group,contrasting to 27 healthy persons.Results The levels of serum TNF-α,IL-6 in the anemic patients group were higher than those in the non-anemic group subjects,but LVEF Wag lower.With the increase of anemia severity,the levels of serum TNF-α,IL-6 significantly increased;there was a positive correlation between LVEF and the levels of serum TNF-α,IL-6(P＜0.01),and a negative correlation between LVEF and Hb concentration.Conclusion The levels of cytokine promote the pathophysiological procedure between cardiac failure and anemic in ICM.