Value of ursodeoxycholic acid for preventing recurrence of bile microlithiasis-associated cholangitis

VernacularTitle:熊去氧胆酸对胆道微结石性胆管炎的预防价值探讨
Author: Yabing HU ; Yunzhi SHEN ; Lu SHEN
Publication Type:Journal Article
Keywords: Cholangitis; Endoscopy; Bile microlithiasis; Ursadeoxychohc acid
From: Chinese Journal of Postgraduates of Medicine 2010;33(2):16-18
CountryChina
Language:Chinese
Abstract: Objective To explore clinical strategies of treating in bile microlithiasis-associated cholangitis and preventing the recurrence of ursodeoxycholic acid(UDCA).Methods Forty-one cases of bile microlthiasis-associated cholangitis from January 2006 to July 2007 Were analyzed and followed up.All patients underwent endoscopic therapy who were divided into UDCA group(21 cases)and non-UDCA group (20 cases)according to the use of UDCA or not besides endoscopic therapy.After using UDCA for 12 months,the complications and the incidence rate of recurrent cholangitis in each group were compared.Results Forty-one cases had no serious complications after endoscopic therapy.None had recurrent cholangitis in UDCA group,4 cases in non-UDCA group got recurrent cholangitis.One case developed pancreatitis.There was statistical significance between the two groups(P=0.021).Conclusion Endoscopic therapy is a safe and effective treatment of bile microlithiasis-associated cholangitis,and UDCA can prevent the recurrent cholangitis effectively after endoscopic therapy.