Monocyte chemotactic protein-1 and ischemic stroke
10.3760/cma.j.issn.1673-4165.2009.12.012
- VernacularTitle:单核细胞趋化蛋白-1与缺血性卒中
- Author:
Liyun SONG
;
Li WANG
- Publication Type:Journal Article
- Keywords:
chemokine CCL2;
atherosclerosis;
stroke;
inflammation
- From:
International Journal of Cerebrovascular Diseases
2009;17(12):944-947
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory reaction plays an important role in the occurrence and development of ischemic stroke. Monocyte chemotactic protein-1 (MCP-1) is one of the subfamily members of the CC chemokine class. It can attract and activate a variety of cells, such as monocytes and T lymphocytes, promote the expression of cytokines, and participate in the occurrence of ischemic brain injury. This article reviews the progresses on the MCP-1 and ischemic stroke-related research.