The roles of amyloid βprotein in neurovascular unit injiny
10.3760/cma.j.issn.1673-4165.2009.12.008
- VernacularTitle:β淀粉样蛋白在神经血管单元损伤中的作用
- Author:
Wei WEI
;
Weiwei ZHANG
- Publication Type:Journal Article
- Keywords:
amyloid βprotein;
cerebral amyloid angiopathy;
Alzheimer disease;
blood-brain barrier
- From:
International Journal of Cerebrovascular Diseases
2009;17(12):926-930
- CountryChina
- Language:Chinese
-
Abstract:
The deposition of amyloid β-protein (Aβ is the key pathological basis of cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD). The current studies emphasis that the stability of internal environment between cells of the neurovascular unit is the key to maintain normal brain function. This article reviews the relationship between the Aβand the neurovascular unit injury, and we expect to provide some new ideas for the clinical prevention and treatment of CAA and AD.
