Association between plasma visfatin and intima-media thickness of carotid artery in patients with type 2 diabetes
10.3760/cma.j.issn.1000-6699.2010.01.004
- VernacularTitle:2型糖尿病患者内脂素水平与颈动脉内中膜厚度相关
- Author:
Lihua GAO
;
Zhansheng ZHAO
;
Hui TIAN
;
Bingjie WU
;
Limei JIA
;
Mian WANG
;
Yonggui DENG
;
Hong ZHOU
;
Lihui ZHANG
;
Shengou SU
- Publication Type:Journal Article
- Keywords:
Visfatin;
Diabetes meilitus;
type 2;
Atherosclerosis;
Intima-media thickness
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(1):15-16
- CountryChina
- Language:Chinese
-
Abstract:
Seventy-three patients with type 2 diabetes mellitus were divided into atheroselerosis(AS) group and non-AS group according to the intima-media thickness(IMT)of the carotid artery.The plasma visfatin level in AS group was higher than that in non-As group[(44.95±10.14 vs 34.52±9.08)μg/L,P<0.05],and both of them were higher than that of the control [(24.46±7.18)μg/L,both P<0.05 ].The visfatin level Was positively correlated with IMT,waist-to-hip ratio,visceral fat thickness,fasting insulin,and HOMA insulin resistance index.Age,duration of diabetes,HbA_(1C),and visfatin level were the major risk factors for IMT of the carotid artery.
