Endothelial progenitor cells and ischemic cerebrovascular disease
10.3760/cma.j.issn.1673-4165.2009.12.010
- VernacularTitle:内皮祖细胞与缺血性脑血管病
- Author:
Jingye LU
;
Guangxi ZHOU
- Publication Type:Journal Article
- Keywords:
endothelial cells;
stem cells;
cerebrovascular disorders;
cerebral ischemia;
neovascularization,physiologic
- From:
International Journal of Cerebrovascular Diseases
2009;17(12):936-939
- CountryChina
- Language:Chinese
-
Abstract:
Endothelial progenitor cells (EPCs) are a precursor cell of endothelium that has the ability of differentiation and proliferation. In given conditions, EPCs can be mobilized to the ischemic tissue to participate in repairing the injured blood vessels and angiogenesis, and EPCs are regarded as a marker of vascular reparative capacity. Studies in recent years have indicated that the changes of EPC number play an important role in the occurrence and prognosis of cerebral ischemia. As a potential therapeutic strategy, EPCs may be used in ischemic cerebrovascular disease. This article reviews the application progress of EPCs in ischemic cerebrovascular disease.
