Hemo oxygenase-1 and its relationship with svere acute pancreatitis
10.3760/cma.j.issn.1673-4203.2010.02.016
- VernacularTitle:血红素加氧酶-1及其与重症胰腺炎之间关系的研究进展
- Author:
Zhiwei WANG
;
Enqiang MAO
- Publication Type:Journal Article
- Keywords:
Heme oxygenase-1;
Pancreatitis;
Acute necrotizing
- From:
International Journal of Surgery
2010;37(2):121-124
- CountryChina
- Language:Chinese
-
Abstract:
Recently, heme oxygenase-1 (HO-1) has been emphasized in the area of intensive care unit (ICU) and other domains. HO-1 can catalyze the decomposition of heine and the products of its enzymatic activity, including carbon monoxide, biliverdin, and bilirubin and ferritin can play a significant cytoprotec-tive role in antagonizing inflammation, protecting cells from oxidative injury and cellular stresses. In the re-search of severe acute pancreatitis (SAP), researchers have realized that it is of great importance to antago-nize the overflow of cytokines in order to improve the therapeutic effect of SAP. In this article, we give a re-view of the research progress of HO-1 and its relationship with SAP.
