P-selectin and ischemic cerebrovascular disease
10.3760/cma.j.issn.1673-4165.2009.12.013
- VernacularTitle:P-选择素与缺血性脑血管病
- Author:
Yajie CHEN
;
Yi YANG
;
Mingshan REN
- Publication Type:Journal Article
- Keywords:
P-selectin;
cerebrovascular disorders;
brain ischemia
- From:
International Journal of Cerebrovascular Diseases
2009;17(12):948-951
- CountryChina
- Language:Chinese
-
Abstract:
P-selectin is also known as CD62. It promotes the occurrence of ischemic cerebrovascular disease by mediating the activation of endothelial cells and platelets as well as the processes of the formation and development of atherogenesis. A number of studies have confirmed that P-selectin plays important roles in the occurrence and development of the risk factors (such as hypertension, diabetes, hypercholesterolemia, heart disease, smoking, alcohol abuse and hyperfibrinogenemia) for ischemic cerebrovascular disease. It remains to be confirmed by further studies whether P-selectin can be used as an independent risk factor for predicting the occurrence of ischemic cerebrovascular disease.
