Current therapeutic options and progress for colorectal liver metastases
10.3760/cma.j.issn.1673-4203.2010.02.011
- VernacularTitle:结直肠癌肝转移的外科治疗现状与进展
- Author:
Yanxin CHANG
;
Jiahe YANG
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
Liver metastasis;
Liver metastasectomy;
Neoadjuvant chemotherapy
- From:
International Journal of Surgery
2010;37(2):105-108
- CountryChina
- Language:Chinese
-
Abstract:
The liver is a primary target organ of colorectal cancer metastases. Surgical resection is pres-ently the only approach that offers patients a substantial chance of cure. Five-year survival ranges 25% -39%. But by the time of diagnosis, only 10% -25% of patients were considered eligible for surgical directed thera-pies. New therapeutic modalities such as ablation, hepatic arterial infusion chemotherapy, neoadjuvant chem-otherapy and targeted therapy present promise for the future treatment of unresectable liver metastases. These treatments and progress in surgical therapy are reviewed in this article.