Initial clinical study of virtual touch quantification for evaluation of hepatic fibrosis of chronic liver disease

VernacularTitle:声触诊组织成像量化技术无创评价慢性肝病肝纤维化程度的初步临床研究
Author: Xinli ZHANG ; Meng LI ; Hui FENG ; Dakun ZHANG ; Ying SU ; Yanxian ZHOU ; Min CHEN ; Xia CHEN
Publication Type:Journal Article
Keywords: Ultrasonography; Liver cirrhosis; Virtual touch quantification
From:Chinese Journal of Ultrasonography 2010;19(1):12-15
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical value of virtual touch quantification (VTQ) technique in assessing the hepatic fibrosis. Methods A total of 115 inpatients with chronic liver disease receiving liver biopsy were enrolled in this study, all patients liver tissue was checked by VTQ technique, and the results were compared with those of the control group including 80 healthy subjects. Results VTQ value was significantly different between the two groups (P = 0.0000).The VTQ value among different degree of hepatic fibrosis but between S0 and S1 had statistical significances (P = 0.0212, P = 0.0000).ROC curve displayed that VTQ value of 1.4 m/s could be used to diagnose middle-high-grade liver fibrosis, the sensitivity and specificity were 85.4 % and 64.7%, respectively. Conclusions VTQ can be used as a noninvasive and effective means for assessing the degree of hepatic fibrosis.