Experimental study of microwave ablation in ex vivo and in vivo livers using a new type of internally cooled microwave antenna: relationship between short-axis diameter of coagulation necrosis and microwave power
10.3760/cma.j.issn.1004-4477.2010.01.023
- VernacularTitle:新型内冷微波天线消融肝组织的实验研究——凝固灶短轴径与功率的关系
- Author:
Nianan HE
;
Wenping WANG
;
Zhengbiao JI
;
Chaolun LI
;
Beijian HUANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microwaves/therapeutic use;
Liver
- From:Chinese Journal of Ultrasonography
2010;19(1):70-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective To probe the correlation between the short-axis diameter(SD) of coagulation necosis and the microwave power(P) using a new type of internally cooled microwave antenna in ex vivo and in vivo liver model.Methods Fourteen microwave ablations were performed in swine livers ex vivo and canine livers in vivo under the microwave powers of 30-90W and the durations of 10 min and 20 min, respectively.The short-axis diameter(SD) and the long-axis diameter(LD) of the coagulation were measured.The difference of SD, LD and SD/LD in swine liver ex vivo and canine liver in vivo were compared.The relationship between the SD and microwave power was analysised using linear regression model.Results Under the same conditions,the SDs and LDs of the coagulations of canine livers in vivo were smaller than those of swine livers in ex vivo (P <0.01).There was such a higher linear relationship(r = 0.96-0.99, P <0.01) between the SD of coagulation and the power in vivo liver model as the results acquired in ex vivo.Conclusions Although the blood flow decreased the SDs of the coagulation of microwave ablation in liver in vivo, but there was still a higher linear relationship between SD and microwave power.
