The echocardiographic diagnostic characteristics and follow-up of apical hypertrophic cardiomyopathy
10.3760/cma.j.issn.0578-1426.2010.02.010
- VernacularTitle:心尖肥厚型心肌病超声诊断特点及随访
- Author:
Chengjian YANG
;
Xinhe YE
;
Xin XU
;
Chunyuan YOU
;
Zhihong LI
;
Dayi HU
- Publication Type:Journal Article
- Keywords:
Cardiomyopathy;
hypertrophic;
Eehocardiography;
Follow-up studies
- From:
Chinese Journal of Internal Medicine
2010;49(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the echocardiographic features of apical hypertrophic cardiomyopathy( ApHCM). Methods Twenty-seven patients with ApHCM including 21 men and 6 women, average age (42.7 ± 5. 1 ) years old were followed up from 1995 to 2008 to investigate the clinical, electroeardiographic and echocardiographic features. Results The major features of ECG were increased R amplitude( V_4 > V_5 > V_3)and inverteted T wave(especially in V_(3-5) leads and the voltage of the inverteted T waves may be up to ≥10 mm). The major feature of echocardiography was the thickening of left ventricular apical wall to 15 - 37 ( 18. 0± 3. 3 ) mm. The final follow up showed that the mean thickness of the apical wall was ( 19. 7 ±3. 7) mm. The ratio of the thickness of left ventricular apical wall to posterior wall before and after the follow up was 1. 7 ±0. 3 and 1. 9 ±0. 9 respectively, with significant statistical difference ( P < 0. 05). There was no difference in the left ventricular end-diastolic dimension and left ventricular ejection fraction. The main cardiovascular events were atrial fibrillation ( 16 cases) , heart failure of NYHA ID-IV class (3 cases) , anterior wall myocardial infarction ( 1 case) and sudden death ( 1 case). Conclusions The final diagnosis of ApHCM depends on the characteristic inverteted T wave in ECG and apical hypertrophy in echocardiography. The prognosis of ApHCM is rather good for its progression is relatively slow.