Clinical study of different dosage of Ketamine Combined with Propofol on painless Induced Abortion

VernacularTitle:不同剂量氯胺酮复合异丙酚用于无痛人工流产术的临床研究
Author: Ningjiang LI ; Lihong SHEN ; Chunhui YUAN ; Enfu GAO ; Lingjian HUANG ; Liang WU
Publication Type:Journal Article
Keywords: Abortion; induced; Ketamine; Propofol
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(1):56-57
CountryChina
Language:Chinese
Abstract: Objective To explore a reasonable and secure anesthesia induction in painless induced abortion.Methods 120 patients of painless induced abortion were randomly divided into six groups,control group was injected with Propofol 3.5mg/kg through vein,besides given Propofol 3.5mg/kg,other 5 groups were injected with ketamine 0.1mg/kg、0.2mg/kg、0.3mg/kg、0.4mg/kg、0.5mg/kg through vein respectively.The parameter of hemodynamics,effect of analgesia,time of unconsciousness,recovery time of consciousness,recovery time of orientation,incidence of respiratory depression,side effect,time of discharge from hospital were observed.Results The recorded time and incidence of side effect have statistical significance between group of ketamine 0.5mg/kg and group of ketamine 0.3mg/ks(P<0.05);effect of analgesia have statistical significance between group of ketamine 0.3mg/kg、0.4mg/kg、0.5mg/kg and control group.Conclusion Ketamine 0.3mg/kg combined with Propofol is an ideal choice of painless induced abortion.