Analysis of the clinical effect of she-saiko-to combined with silymarin on liver fibrosis due to chronic hepafitis B

VernacularTitle:小柴胡汤联合水飞蓟素治疗慢性乙型肝炎肝纤维化疗效分析
Author: Bing QIU ; Peiyi ZHANG ; Xiaoyan TANG ; Qinghua LI ; Dongfu LI
Publication Type:Journal Article
Keywords: Hepatms B; chronic; Sho-saiko-to; Silymarin
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(1):38-39
CountryChina
Language:Chinese
Abstract: Objective To evaluate the therapeutic effect of sho-saiko-to silymarin on liver fibrosis due to chronic hepatitis B.Methods 90 patients with liver fibrosis due to chronic hepatitis B virus(HBV) were randomly divided into therapy group and control group.50 patients in therapy group were given sho-saoko-to and silymarin;While 40 patients in control group were given silymarin only,they were all treated for 6 months.The changes were observed including liver function,serum liver fibrosis and virology indexes before and after treatment in two groups.Resuits Indexes of liver function and serum liver fibrosis in therapy group were improved obviously(P<0.05 or P<0.01),while better clearance to HBV is comparable to control group(P<0.05).Conclusion The treatment with sho-saiko-to combined silymarin on liver fibrosis due to chronic hepatitis B had explicit clinical effect.