Limited significance of frozen section analysis in nephron sparing surgery
10.3760/cma.j.issn.1671-7368.2010.02.024
- VernacularTitle:保留肾单位手术术中切缘冰冻病理与术后病理对比分析
- Author:
Lei SHAN
;
Tianzhong YAN
;
Xiangyang WANG
;
Qizhong LI
- Publication Type:Journal Article
- Keywords:
Carcinoma,renal cell;
Nephrectomy
- From:
Chinese Journal of General Practitioners
2010;9(2):131-132
- CountryChina
- Language:Chinese
-
Abstract:
One hundred sixty-three cases with a mean age of 58 years (range 21 to 87) underwent nephron sparing surgery due to suspected renal tumors.Mean tumor size was 2.8 cm (range 1.0 to 4.0 cm).Frozen section analysis was routinely performed during surgery,positive tumor margins in frozen section analysis were found in 5 cases (3.1%),and immediate radical nephrectomy was followed.Among 158 cases,in which frozen section analysis showed negative margins,paraffin sections disclosed positive tumor margins in 6 cases (3.8%).Our results suggest that frozen section analysis during nephron sparing surgery has limited clinical significance and hence routine incorporation in urological practice should be reconsidered.