Association of interleukin-6 receptor gene polymorphism with obesity
10.3760/cma.j.issn.1000-6699.2010.02.009
- VernacularTitle:白细胞介素6受体基因多态性与肥胖的关联研究
- Author:
Caifeng YAN
;
Hongding XIANG
;
Wei CHEN
;
Fan PING
;
Min YANG
- Publication Type:Journal Article
- Keywords:
Interleukin-6 receptor gene;
Polymorphism,single nucleotide;
Waist circumference;
Body mass index
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(2):125-126
- CountryChina
- Language:Chinese
-
Abstract:
To examine the relationship between genetic variants in the interleukin-6 receptor gene and obesity. The result showed that the carriers of Asp358 homozygotes had higher risk in developing obesity when compared with Ala358 homozygotes (OR = 1.32,95% CI 1.07-1.68, P = 0. 041). Interleukin-6 receptor gene pulymorphism was significantly associated with obesity.