MRI findings of fetal cleft lip and palate
10.3760/cma.j.issn.1005-1201.2010.02.011
- VernacularTitle:胎儿唇腭裂的MRI表现
- Author:
Guangbin WANG
;
Liguang CHEN
;
Xiangyu ZHU
;
Cuiyan WANG
;
Yinghua ZHANG
;
Lijuan WANG
;
Huihua LI
;
Xiuling QIU
;
Lei QU
;
Yulong WEI
;
Rui DING
;
Xueqin SUN
- Publication Type:Journal Article
- Keywords:
Fetus;
Cleft lip;
Magnetic resonance imaging;
Cleft palate
- From:
Chinese Journal of Radiology
2010;44(2):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the MR findings of fetal cleft lip (CL) and evaluate the advantages and limitations of MRI in the diagnosis. Methods Twelve pregnant women suspicious of fetal CL/cleft palate(CP) on ultrasonography were enrolled in the study. The findings of ultrasonography, MRI and following-up were compared. Results MRI and ultrasonography detected 12 fetuses with CL/CP. The following-up results showed 1 case with incomplete cleft lip and the other 11 cases with complete cleft lips and cleft palates. MRI and unltrasonography were consistent with the follow-up in CL detection, showing completed or uncompleted soft tissue interruption of the fetal lips with amniotic fluid filling which is high signal on T_2WI. On MRI, CP showed discontinuous of the soft tissue which were interrupted by long T_2 signal and communicating with oral cavity and nasal cavity. MRI missed 1 case and excluded 1 case of CP. Ultrasonography predicted 5 case of CL, excluded 1 CP but missed 6 cases. The accuracy, sensitivity and specificity in detection CL/CP was 91.7% (11/12), 90.9% (10/11), 100% (1/1) for MRI and 50.0% (6/12),45.5% (5/11), 100% (1/1) for ultrasonography, respectively. Conclusion MR imaging had advantage over ultrasonography in detecting CP, MRI is an essential when CP is suspicious on ultrasonography.