Clinical features and pregnancy outcomes of early-onset severe pre-eclampsia

VernacularTitle:早发型重度子痫前期的临床特点和妊娠结局分析
Author: Wei WEI ; Hong YU ; Yang SHEN ; Mulan REN
Publication Type:Journal Article
Keywords: Early-onset severe preeclampsia; Complication; Peri-natal outcome
From: Clinical Medicine of China 2010;26(2):161-164
CountryChina
Language:Chinese
Abstract: Objective To explore clinical features and pregnancy outcomes of early-ouset severe pre-eclampsia. Methods Clinical data of 96 cases of severe preeclampsia who deliveried in Southeast University from November 2004 to February 2009 were analyzed. The patients were divided into two groups, early-onset preeclampsia group(onset gestatioual weeks <34) and later-onset preeclampsia group(onset gestatianal weeks≥34 ). Resnits Significant difference of two groups were found in central nervous system symptom and urine protein (+ +) or > 2 g/24 h (P<0.05), incidence of abnormal prenatal outcome (χ~2=14.792,4.741,27.03 respectively;P<0.05). Mean birth weight in early-onset preeclampsia group (1743.86±630.34)g was lower than that in later-onset pre-eclampsia greup(2940.47±762.36)g (t=6.71 ,P<0.05). Conclusions Clinical symptoms of early-onset severe preeclampsia are severe , and have a higher incidence of abnormal prenatal outcomes. Prevention, prediction ,diagno-sis and management of preeclampsia are important for mothers and children.