Correlation between the severity of coronary artery disease with serum bilirubin and left ventricular cardiac function
10.3760/cma.j.issn.1008-6315.2010.02.009
- VernacularTitle:冠状动脉病变程度与血清胆红素及左心功能的相关性研究
- Author:
Ge TIAN
;
Yuelan ZHANG
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Bilirubin;
Gensini's score;
Left ventricular cardiac function;
Correlation
- From:
Clinical Medicine of China
2010;26(2):136-138
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the severity of coronary artery disease with se-rum bilirubin and left ventricular cardiac function. Methods Two hundred and six patients underwent blood bio-chemical ,color-echocardiography and angiography of coronary artery. The patients were divided into 4 ordinal groups according to the Gensini score indicating the severity of coronary artery disease. Results There were significant differences in total bilirubin(TBIL), left atrial dimension (LAD), left ventricular dimension (LVD) and left ventric-ular ejection fraction (LVEF) between the four groups(P<0.05 or P<0.01). The Spearman correlation coefficent between Gensini's scores and LAD, LVD were 0.280 (P=0.000) and 0.176 (P=0.011), respectively. The Spearman correlation coefficient between Gemini's scores and TBIL, LVEF were -0.541 (P<0.000) and -0.222 (P=0.001), respectively. The multiple linear regression between the Gensini's score and parameters showed that TBIL and LVD were independently correlated with the Gensini scores (P=0.000 and P=0.002, respec-tively). Conclusions TBIL and LVD were independently correlated with Gensini's score. LVEF was negatively cor-related with the severity of coronary disease and is a useful predictor for the severity of coronary atherosclerotic heart disease.
