Liver Abscess by Aspergillus and Enterococcus faecium in a Patient with Acute Myeloid Leukemia: A Case Report and Literature Review.
- Author:
Kyung Wook HONG
1
;
Jae Cheol KWON
;
Hyun Ji CHUN
;
Dong Gun LEE
;
Hee Je KIM
;
Woo Sung MIN
Author Information
- Publication Type:Case Report
- Keywords: Aspergillosis; Enterococcus; Liver abscess; Acute myeloid leukemia
- MeSH: Abdominal Pain; Abscess; Anti-Bacterial Agents; Aspergillosis; Aspergillus; Drainage; Enterococcus; Enterococcus faecium; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Korea; Leukemia, Myeloid, Acute; Liver; Liver Abscess; Pyrimidines; Remission Induction; Triazoles
- From:Infection and Chemotherapy 2011;43(4):377-381
- CountryRepublic of Korea
- Language:Korean
- Abstract: We report a case of liver abscess caused by Aspergillus and Enterococcus faecium in a patient with acute myeloid leukemia. As far as we know, this is the first case of hepatic aspergillosis in Korea. After remission induction chemotherapy, the female patient presented with abdominal pain and was found to have liver abscess. The patient was treated with antibiotics against E. faecium, which was isolated from the abscess drainage. However, the therapeutic response was unsatisfactory and a left lateral sectionectomy of the liver was conducted after 21 days of treatment. The liver tissue showed typical pathologic findings of aspergillosis and voriconazole was administered. Allogeneic hematopoietic stem cell transplantation was performed successfully after 4 months. The possibility of aspergillosis should be considered when an immunocompromised patient with hepatic abscess poorly responds to the use of broad spectrum antibiotics.
