The multisection spiral CT perfusion imaging on acute pancreatitis and correlated with clinical criteria
10.3760/cma.j.issn.1674-1935.2009.04.007
- VernacularTitle:急性胰腺炎多层螺旋CT灌注参数与临床病情评估系统的关系研究
- Author:
Fangjun WANG
;
Pengfei LIU
;
Weichang CHEN
;
Liang GUO
;
Xiangming FANG
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Tomography,X-ray computed;
Hemoperfusion
- From:
Chinese Journal of Pancreatology
2009;9(4):238-240
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the blood perfusion characteristic of acute pancreatitis (AP) using multisection dynamic CT. To detect the changes of the perfusion parameters in patients with AP and assess the value of the perfusion parameters as severity indicators in AP. Methods 120 cases (34 cases of normal pancreas and 86 cases of AP) were examined for pancreatic perfusion from August 2006 to April 2008. The multisection dynamic CT perfusion series was performed by a multisection CT scanner (Siemens somatom Sensation 64) and the perfusion parameters, including BF, BV, TTP, PS, were collected and were compared with APACHE Ⅱ score, Ranson score, CRP, CTSI, time to abdominal pain cessation, length of hospital stay and complication rate for correlation analysis. Results The mean BF, BV, TTP and PS in AP patients were (113.57 ±50.04) ml · 100 mg~(-1) · min~(-1), (146.61 ±45.11) ml/L, (148. 88 ±21. 16) 0.1 s, (119.53± 52.36) 0. 5 ml · 100 ml · min , respectively; when compared with normal control, BF, BV decreased significantly (P<0.05) , while the change of TTP, PS were not statistically significant. Both BF and BV were correlated with APACHE II score, Ranson score, CRP, CTSI (P<0. 05) , as well as the time to abdominal pain cessation, length of hospital stay and complication rate (P < 0. 05). Conclusions Pancreatic vessel perfusion was decreased in AP. Both BF and BV were correlated with APACHE Ⅱ score and Ranson score, CRP, CTSI, and could be used to predict severity of acute pancreatitis.
