Function of Cbl-b gene in anti-tumor immunity of peripheral blood CD8+T cells
10.3760/cma.j.jssn.1673-422X.2009.11.009
- VernacularTitle:Cbl-b 基因在外周血 CD8~+T 细胞抗肿瘤免疫中的作用
- Author:
Xuefeng LI
- Publication Type:Journal Article
- Keywords:
T-lymphocytes;
Neoplasms;
Immunity;
Cbl-b
- From:
Journal of International Oncology
2009;36(11):827-830
- CountryChina
- Language:Chinese
-
Abstract:
Cbl-b (Casitas B cell lymphoma-b ) gene is a member of the cbl family,and the Cbl-b pro-tein plays an important role in regulating anti-tumor immunity by interacting with the signal transduetion pro-tein. Silencing Cbl-b expression in peripheral blood T cells by gene interference technology can regulate body's anti-tumor immunity.It is expected to achieve a major breakthrough in cancer therapy.
