Therapeutic effects of teimisartan on microinflammation in maintenance hemodialysis patients
10.3760/cma.j.issn.1008-6315.2010.01.012
- VernacularTitle:替米沙坦对维持性血液透析患者微炎症状态的影响
- Author:
Jun LIANG
- Publication Type:Journal Article
- Keywords:
Timisartan;
Maintenance hemodialysis;
Micminflammation
- From:
Clinical Medicine of China
2010;26(1):30-31
- CountryChina
- Language:Chinese
-
Abstract:
Objeetive To investigate the effects of timisartan on microinflammation state in maintenance bemodialysis patients.Methods In 40 maintenance hemodialysis patients and 20 healthy control subjects, the levels of C-reactive protein(CRP),interlukin-6(IL-6),tumor necroais factor alpha(TNF-α)were measured,the 40 maintenance bemodialysis patients were randomly divided into 2 groups to receive timisartan 80 mg daily or non-timisartan theraphy.All above parametes were assayed again after 24 weeks.Results Compared with healthy people,the serum CRP,IL-6,TNF-α were elevated significantly in patients with maintenance hemodialysis.After 24 weeks treatment,the levels of CRP,IL-6,TNF-α in Timisartan group was lower than before,and the levels of CRP, IL-6, TNF-α were much lower in timisartan group than non-timisartan group(P<0.01).Conclusions Timisartan can relieve the microinflammation state in maintenance hemodialysis patients.
