The expression and meaning of bcl-xL in superficial bladder tumor

VernacularTitle:bcl-xL在浅表性膀胱肿瘤中的表达及意义
Author: Bing CAI ; Wei WU ; Yeping LI ; Yirong ZHANG
Publication Type:Journal Article
Keywords: Urinary bladder neoplasms; Prognosis; bcl-x protein
From: Chinese Journal of Postgraduates of Medicine 2010;33(5):15-17
CountryChina
Language:Chinese
Abstract: Objective To investigate the relations of the expression of bcl-xL in superficial bladder tumor and prognosis. Method The expression of bcl-xL was detected by envision system in 80 cases of superficial bladder tumor. Results In patients with high expression of bcl-xL, the recurrence rate was higher than that of normal expression [71.4%(30/42) vs 50.0%(19/38) ,P < 0.05], and the recurrence of time as early as normal expression [(16.0 ± 1.2) months vs (36.0 ± 4.5) months](P < 0.05). Conclusion The expression of bcl-xL could effectively predict the prognosis of patients with bladder tumor, those who with high expression of-bcl-xL have bad prognosis.