The expression and meaning of bcl-xL in superficial bladder tumor
10.3760/cma.j.issn.1673-4904.2010.05.006
- VernacularTitle:bcl-xL在浅表性膀胱肿瘤中的表达及意义
- Author:
Bing CAI
;
Wei WU
;
Yeping LI
;
Yirong ZHANG
- Publication Type:Journal Article
- Keywords:
Urinary bladder neoplasms;
Prognosis;
bcl-x protein
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(5):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relations of the expression of bcl-xL in superficial bladder tumor and prognosis. Method The expression of bcl-xL was detected by envision system in 80 cases of superficial bladder tumor. Results In patients with high expression of bcl-xL, the recurrence rate was higher than that of normal expression [71.4%(30/42) vs 50.0%(19/38) ,P < 0.05], and the recurrence of time as early as normal expression [(16.0 ± 1.2) months vs (36.0 ± 4.5) months](P < 0.05). Conclusion The expression of bcl-xL could effectively predict the prognosis of patients with bladder tumor, those who with high expression of-bcl-xL have bad prognosis.