Application of adipose-derived mesenchymal cells in bone/cartilage/intervertebral disc/tendon tissues repair

VernacularTitle:脂肪来源干细胞在骨/软骨/椎间盘/肌腱组织修复中的应用
Author: Dan DENG ; Wei LIU ; Yilin CAO
Publication Type:Journal Article
Keywords: Adipose-derived stem cells; Orthopaedic tissue regeneration; Differentiation
From: International Journal of Biomedical Engineering 2009;32(6):363-366
CountryChina
Language:Chinese
Abstract: Autologous cells of bone, cartilage, intervertebral disc and tendon, are hard to be cultured and proliferate in vitro and thus have difficulty to be introduced in the repair of damaged tissue. Stem cells have the ability to self-renew and differentiate into many tissue types. Recent progress in stem cell research has led to an enthusiastic effort to utilize stem cells for orthopaedic tissue regeneration. Due to the abundance and easiness of harvest, adipose-derived mesenchymal celI(ASC) is an attractive, readily available aduh stem cell that has become increasingly popular for use in stem cell and tissue engineering applications. This review focuses on the use of ASC in orthopaedic tissue repair. Recent results from in vivo defect repair utilizing ASC suggested the great potential of ACS in clinical orthopaedic tissue regeneration.