Feature of clinic and imageology in patients with unstable angina pectoris after radiation therapy to chest
10.3760/cma.j.issn.1673-4904.2009.31.010
- VernacularTitle:经胸放射治疗后的不稳定型心绞痛患者冠状动脉影像学及临床特点分析
- Author:
Chunxing SUI
;
Wenmin LIU
;
Xuchen ZHOU
;
Xiaoqun ZHENG
- Publication Type:Journal Article
- Keywords:
Angina,unstable;
Radioactivity;
Heart diseases;
Brain natriuretic peptide
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(31):26-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe feature of clinic and imageology in patients with unstable angina pectoris after radiation therapy to chest. Methods The study enrolled 58 patients who had unstable angina pectoris. Twenty-eight patients were in the postradiation therapy to chest group, 30 patients were in the common unstable angina pectoris group. All patients underwent multislice spiral CT(MSCT) examination and coronary angiography (CAG). After one year follow-up, the levels of brain natriuretic peptide (BNP) and ventricular wall motion score index (WMSI) were measured , the incidence of cardiovascular events were observed in all patients. Results Calcific, multi-vessel, thrombotic disease and dissection were significantly different between the two groups, when one year follow-up , the levels of BNP were higher in the postradiation therapy to chest group than those in the common unstable angina pectoris group [ (234.31 ± 121.39) ng/L vs (124.74 ±37.81) ng/L] WMST, incidence of the first heart failure, angina pectoris recurrence and revascularization were significantly different too (P< 0.05 ). Conclusions The complex lesions are major in the postradiation therapy to chest. Moreover, because radiation injures the heart valves and myocardium,these patients' long-term prognosis are worst.
