Analysis of the risk factors for neonatal ventilator-associated pneumonia

VernacularTitle:新生儿机械通气相关性肺炎危险因素探讨
Author: Hua WU ; Xiangrong LI ; Xiaoyun CHEN
Publication Type:Journal Article
Keywords: Neonate; Ventilator-associated pneumonia; Risk factor
From: Chinese Pediatric Emergency Medicine 2010;17(1):20-22
CountryChina
Language:Chinese
Abstract: Objective To explore the risk factors of ventilator-associated pneumonia(VAP)in neonatal patients.Methods A retrospective study was conducted on the 82 neonates who had ever received mechanical ventilation for more than 48 hours,non-conditional logistic regression analysis was performed to determine independent predictors for VAP.Results By logistic regression analysis,the following risk factors independently predicted VAP:gestational age(OR = 6.209,95%CI =2.112～16.835),duration of mechanical ventilation(OR =5.842,95%CI = 1.366～14.936),times of endotracheal suctioning(OR =4.764,95%CI = 1.416～14.736),re-intubation(OR = 6.190,95%CI = 1.669～16.019),gastric tubes retention(OR =6.794,95%CI = 1.928～19.160),treatment with CNS suppressant(OR = 4.297,95%CI = 1.002～15.216).Conclusion The neonatal VAP occoured for multiple facors,the rsik factors include gestational age,duration of mechanical ventilation,endotracheal suctioning,re-intubadon,gastric tubes retention and treatment with CNS suppressant.