Clinical analysis on the level of serum ferritin in patients with severe hepatitis B
10.3760/cma.j.issn.1008-6706.2009.12.001
- VernacularTitle:重型乙型肝炎血清铁蛋白水平分析
- Author:
Ruilie CHEN
;
Xiaodan ZHENG
;
Genglong GUO
;
Shaorui LIN
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Ferritins
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(12):2113-2114
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between the level of serum ferritin(SF) and the degree of liver damagement with severe hepatitis B,and the clinical significance of SF changes in judging the prognosis.Methods The level of SF was detected by radioimmunoassay(RIA) from 62 cases with severe hepatitis B,the level of SF from acute hepatitis B,chronic hepatitis B,liver cirrhosis and normal men were served as contrast study.Results The level of SF from severe hepatitis B was significantly higher than those from acute hepatitis B,chronic hepatitis B,liver cirrhosis and normal men;the level of SF was positively correlated with total bilirubin(TB),prothrombin time(PT),total bile acid(TBA) and negatively with Alb,ALT,AST,CHE.The levels of SF of those who died were significantly higher than those of suvivals;the level of SF decreased as the disease controlled and increased as the disease deterio-rated.Conclusions There is a parallel correlationship between the level of SF and the degree of liver damagement with severe hepatitis B,the severer the hepatocyte damage was,the higher the ferritin was.It is helpful to judge the degree of damagement and prognosis of severe hepatitis by detecting the level of serum ferritin.
