Hypertension, depression and cognitive function impairment in elderly
10.3760/cma.j.issn.1008-1372.2010.01.015
- VernacularTitle:老年人高血压、抑郁与认知功能减退的相关性研究
- Author:
Peiyun WANG
;
Hong YAN
;
Yuan ZHONG
;
Gaozhong HUANG
;
Liang CUI
;
Jun JIN
- Publication Type:Journal Article
- Keywords:
Hypertension/CO;
Depression/CO;
Cognition disorders/ET
- From:
Journal of Chinese Physician
2010;12(1):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between hypertension, depression and cognitive function in elderly. Methods General conditions and health status were surveyed in 207 individuals, which were divided into hypertension group, depression group, hypertension and depression group and controls. Patients cognitive function was assessed by the mini-mental state examination (MMSE), depression severity was detected by Hamilton rating scale for depression (HAMD) , other relative data were collected. Results Elderly patients with depression were more inclined to live alone. Comparing with control, hypertension patients had lower attention and calculation. Depression patients had lower orientation, attention, calculation and linguistic ability ( P < 0.05). Compared with hypertension patients, patients combined with depression had significantly lower MMSE scores, orientation, recall and language ( P <0. 05). Patients with hypertension and depression had lower attention and calculation, compared with hypertension a-lone patients ( P <0. 05 ). MMSE scores of depressed patients were negatively related to HAMD scores ( r = -0. 706, P <0.01). Logistic regression revealed depression or combination of hypertension and depression were related to impairment of cognitive ability ( P < 0.01). Conclusion Both hypertension and depression in the elderly impaired cognitive function. The cognitive function impairment in elderly was closely associated with hypertension and depression. Prevention and control of hypertension and depression might be helpful in slowing down impairment of cognitive function in elderly.
