Early nutritional programming and later obesity
10.3760/cma.j.issn.1673-4408.2010.01.017
- VernacularTitle:早期营养程序化与远期肥胖
- Author:
Miao HOU
;
Xiaonan LI
- Publication Type:Journal Article
- Keywords:
Early nutrition;
Programming;
Obesity;
Metabolic syndrome
- From:
International Journal of Pediatrics
2010;37(1):52-55
- CountryChina
- Language:Chinese
-
Abstract:
Epidemiological studies indicate that obesity is associated with metabolic disorders, such as type 2 diabetes hyperlipidemia and hypertension. Early nutrition, especially during pregnancy and lactation can lead to the permanent programming of system by some adaptive effects in physiological, cellular and molecular levels. These adaptive effects persistently changed the metabolic throughout life, hence resulted in increased risk of obesity and metabolic related disease.This review focuses upon the influence of nutrition in early life on adulthood obesity and researches on their pathophysiological mechanism .