Cutaneous phaeohyphomycosis caused by Veronaea botryose Ciferri et Momtemartini: a case report
10.3760/cma.j.issn.0412-4030.2010.03.003
- VernacularTitle:葡萄孢佛隆那霉引起皮肤暗色丝孢霉病一例
- Author:
Suquan HU
;
Xiaofang LI
;
Yanning XUE
;
Xuesi ZENG
;
Guixia Lü
;
Yongnian SHEN
;
Zehu LIU
;
Hong WANG
;
Weida LIU
- Publication Type:Journal Article
- Keywords:
Veronaea botryosa;
Phaeohyphomycosis;
Itraconazole
- From:
Chinese Journal of Dermatology
2010;43(3):153-155
- CountryChina
- Language:Chinese
-
Abstract:
A 16-year-old woman presented plaques on the left auricle and face over a period of 3 years. Fungal culture grew black-grey or dust velvety colony on Sabouraud's dextrose agar plate. A slide culture on potato dextrose agar plate showed conidiophores which were unbranched or occasionally loosely branched. The conidia were sympodial, zero- to two- septate, with rounded apices and truncated bases. The optimum growth temperature was 26℃ - 30℃. The fungus had the ability to liquefy glutin and hydrolyze starch. Anti-fungal susceptibility test showed the fungus was susceptible to itraconazole, terbinafine and amphoterecin B, but resistant to fluconazole. Cutaneous biopsy specimens revealed brown hyphae and budding yeast cells. The sequence of internal transcribed spacer (ITS) 1-ITS4 region of the isolate rDNA was assessed and compared against the Genebank databases. A 99% consistence was observed in the ITS sequence between clinical isolate and reference strain of Veronaea botryose Ciferri et Momtemartini. Based on the above findings, the mold was identified as Veronaea botryose Ciferri et Momtemartini. The lesions gradually subsided after 8-month treatment with oral itraconazole of 100 mg twice daily.
