Progress in pathogenesis of patent ductus arteriosus in preterm infants
10.3760/cma.j.issn.1673-4408.2010.01.009
- VernacularTitle:早产儿动脉导管未闭发病机制的研究进展
- Author:
Wenqing YANG
;
Changyi YANG
;
Hanqiang CHEN
- Publication Type:Journal Article
- Keywords:
Infant,premature;
Patent ductus arteriosus;
Ion channels;
Vasoactive substances
- From:
International Journal of Pediatrics
2010;37(1):26-29
- CountryChina
- Language:Chinese
-
Abstract:
Patent ductus arteriosus(PDA) is a common condition in the premature infants. It is associated with an increase in mortality and sequelae in these infants. The various factors contributing to an patency of the ductus arteriosus in the preterm infants are involved in: insufficient histological development of ductus arteriosus, failure of remodeling theductus, abnormal sensitivity of the ductus to oxygen and vasoactive substances,and genes.