Nodal Stations and Diagnostic Performances of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Patients with Non-Small Cell Lung Cancer.
10.3346/jkms.2012.27.1.46
- Author:
Byung Woo JHUN
1
;
Hye Yun PARK
;
Kyeongman JEON
;
Won Jung KOH
;
Gee Young SUH
;
Man Pyo CHUNG
;
Hojoong KIM
;
O Jung KWON
;
Joungho HAN
;
Sang Won UM
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sangwonum@skku.edu
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration;
Lymph Nodes;
Mediastinum;
Non-Small Cell Lung Cancer
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Biopsy, Needle;
Bronchoscopy;
Carcinoma, Non-Small-Cell Lung/*diagnosis/pathology/ultrasonography;
Endosonography;
Female;
Humans;
Lung Neoplasms/*diagnosis/pathology/ultrasonography;
Lymph Nodes/pathology;
Lymphatic Metastasis;
Male;
Mediastinum/pathology;
Middle Aged;
Neoplasm Staging;
Positron-Emission Tomography and Computed Tomography;
Predictive Value of Tests;
Retrospective Studies;
Sensitivity and Specificity
- From:Journal of Korean Medical Science
2012;27(1):46-51
- CountryRepublic of Korea
- Language:English
-
Abstract:
There are no accurate data on the relationship between nodal station and diagnostic performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). We evaluated the impact of nodal station and size on the diagnostic performance of EBUS-TBNA in patients with non-small cell lung cancer (NSCLC). Consecutive patients who underwent EBUS-TBNA of mediastinal or hilar lymph nodes for staging or diagnosis of NSCLC were included in this retrospective study. Between May 2009 and February 2010, EBUS-TBNA was performed in 373 mediastinal and hilar lymph nodes in 151 patients. The overall diagnostic sensitivity, specificity, accuracy and negative predictive value (NPV) of EBUS-TBNA were 91.6%, 98.6%, 93.8%, and 84.3%, respectively. NPV of the left side nodal group was significantly lower than those of the other groups (P = 0.047) and sensitivity of the left side nodal group tended to decrease (P = 0.096) compared with those of the other groups. Diagnostic sensitivity and NPV of 4L lymph node were 83.3% and 66.7%, respectively. However, diagnostic performances of EBUS-TBNA did not differ according to nodal size. Bronchoscopists should consider the impact of nodal stations on diagnostic performances of EBUS-TBNA.
