Brain activation of acupuncture stimulation at Zusanli acupoint on heroin addicts

VernacularTitle:针刺足三里穴对海洛因成瘾患者脑区激活的影响
Author: Sheng LIU ; Wenhua ZHOU ; Zhi YANG ; Longhui LI ; Guodong YANG
Publication Type:Journal Article
Keywords: Acupuncture/electroacupuncture; fMRI; Addiction,heroin
From: Chinese Journal of Behavioral Medicine and Brain Science 2010;19(2):121-123
CountryChina
Language:Chinese
Abstract: 0bjective To observe the different brain activation of acupuncture and electroacupuncture on healthy subjects and healthy subjects.Methods The different brain activation involved in heroin addiction between healthy subjects and addicts was detected by fMRI.Acupuncture point used in present study Was Zusanli (ST 36).Results Different brain activations between healthy subjects and addicts during electroacupuncture were hypothalamus(X0,Y2,Z9,t=7.36,P<0.01),anterior cingulate(X5,Y49,Z8,t=4.11,P<0.01),tempo-ral gyrus(X61,Y12,Z8,t=3.05,P<0.01).The difference of activated regions during conventional acupuncture between healthy subjects and heroin addicts was thalamus(X2,Y16,Z12,t=2.87,P<0.01),parahippocampus (X17,Y52,Z3,t=3.14,P<0.01),and hypothalamus(X0,Y2,Z9,t=6.98,P<0.01).Conclusion Regions with significant activation detected by fMRI are different during acupuncture in heroin addicts and in the healthy subjects.Notably,the hypothalamus activation is more robust in the addicts than in the healthy subjects during ac-upuncture stimulation.