Lower Residual Renal Function is a Risk Factor for Depression and Impaired Health-Related Quality of Life in Korean Peritoneal Dialysis Patients.
10.3346/jkms.2012.27.1.64
- Author:
Hayne Cho PARK
1
;
Hajeong LEE
;
Jung Pyo LEE
;
Dong Ki KIM
;
Kook Hwan OH
;
Kwon Wook JOO
;
Chun Soo LIM
;
Yon Su KIM
;
Curie AHN
;
Yun Kyu OH
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. yoonkyu@snu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Peritoneal Dialysis;
Depression;
Health-Related Quality of Life;
Residual Renal Function;
Beck's Depression Inventory;
KDQOL-SF
- MeSH:
Adult;
Aged;
Demography;
Depression/*etiology;
Female;
Health Status;
Hemoglobins/analysis;
Humans;
Kidney Diseases/*complications/physiopathology/*psychology;
Male;
Middle Aged;
Peritoneal Dialysis;
*Quality of Life;
Republic of Korea;
Retrospective Studies;
Risk Factors;
Serum Albumin/analysis;
Software
- From:Journal of Korean Medical Science
2012;27(1):64-71
- CountryRepublic of Korea
- Language:English
-
Abstract:
We retrospectively evaluated demographic and biochemical parameters associated with depression and health-related quality of life (HRQOL) in maintenance peritoneal dialysis (PD) patients. This study included 105 patients maintaining PD at Seoul National University Hospital. Data were collected from electronic medical record. Korean Beck's Depression Inventory and Korean version of Kidney Disease Quality of Life short form, version 1.3 were used to evaluate depression and HRQOL, respectively. Moderate to severe depression was found in 24.8% of patients. Patients with lower normalized protein equivalent of nitrogen appearance (nPNA) (< 1.2 g/kg/day), lower weekly renal Kt/V(urea) (< 0.2), and lower serum albumin level (< or = 4.0 g/dL) were associated with depression (P < 0.05). Among them, lower weekly renal Kt/V(urea) was the only independent risk factor associated with depression (OR = 3.1, P = 0.007). Depressed patients showed significantly lower scores in every dimension of HRQOL (P < 0.001). Lower weekly renal Kt/V(urea) (beta = 0.24, P = 0.005) and lower nPNA (beta = 0.15, P = 0.03) were the independent risk factors associated with lower kidney dialysis component summary, whereas lower plasma hemoglobin level was the consistent risk factor for lower physical component summary (beta = 0.22, P = 0.03) and mental component summary (beta = 0.22, P = 0.01). Depression is a prevalent psychological problem in PD population. Residual renal function is the most important factor associated with depression and impaired HRQOL in PD patients.
