Change of the declarative memory in patients with the calcification of the pallidum

VernacularTitle:生理性苍白球钙化患者陈述性记忆的改变
Author: Hui TONG ; Chuanjun WU ; Jianming ZHANG ; Wei HE ; Ruogu HUANG
Publication Type:Journal Article
Keywords: Pallidum; Declarative memory
From: Chinese Journal of Behavioral Medicine and Brain Science 2010;19(2):146-148
CountryChina
Language:Chinese
Abstract: Objective To study change of the declarative memory in patients with the calcification of the pallidum.Method The Chinese version of Wechsler Memory Scale(WMS-RC)test and dmwing forgetting curve were applied in 30 patients and 30 normal controls.Results There was no differences in the WMS-CR test's scores between the two groups.The patients had poorly memory preservation rate at the delays of 2 hours((64.10±0.87)%Vs(44.83±1.57)%,P<0.01),despite normal memory preservation rate over 30 mins and the similar slope after the delays of l day in the forgetting curve.There were negative correlations between the size of calcification and the memory preservation rate at the delays of 2 hours and 9 hours(r=-0.743,r=-0.483.P<0.01).Conclusion The results may reflect the effect of the pallidum on"slower confiolidation"declamtive memory process which aroused by a consequence of the repeated firing of hippocampal-neocortieal connections while the patients have normal memory encoding and retrieval.