Advancement of the relationship between PPARγ and asthma
10.3760/cma.j.issn.1673-4408.2010.01.008
- VernacularTitle:过氧化物酶增殖活化受体γ与哮喘相关性研究进展
- Author:
Shengmei LI
;
Weiping CHEN
;
Chaobin SHEN
- Publication Type:Journal Article
- Keywords:
Asthma;
Peroxisome proliferator-activated receptor γ;
Airway hyperresponsiveness;
Airway inflammation
- From:
International Journal of Pediatrics
2010;37(1):23-25
- CountryChina
- Language:Chinese
-
Abstract:
Peroxidsome proliferator-activated rreceptor γ(PPARγ) has characteristics of regulation of adipocyte differentiation and lipid metabolism.In recent years,more and more evidences suggest that PPARγ plays an important role in the regulation of immune and inflammatory response.The PPARγ expression increased in airway of asthma patients, and PPARγ was involved in airway inflammation and airway hyperresponsiveneas. Recent studies have shown that PPARγ ligands may have a role in the treatment of asthma.
