The function of EB virus specific cytotoxic T lymphocytes after primary infection
10.3760/cma.j.issn.1673-4408.2010.01.010
- VernacularTitle:原发性EB病毒感染后特异性T细胞免疫功能的研究进展
- Author:
Yao YAO
;
Zhengde XIE
;
Kunling SHEN
- Publication Type:Journal Article
- Keywords:
Epstein-Barr virus infections;
T-lymphocytes,Cytotoxic;
Children
- From:
International Journal of Pediatrics
2010;37(1):29-32
- CountryChina
- Language:Chinese
-
Abstract:
After primary EB virus(EBV) infection there are expansions of EBV-specific CD8~+/CD4~+ CTLs responses against lytic peptides and latent peptides in order to control EBV infection. Clinical manifestations of EBV infection are diverse.Its pathogenesis is not clear. The surveillance of EBV specific-immunity plays an important role to control viral replication.There are differences between the CTL responses against lytic peptides and latent peptides. And the migration and activation of EBV specific CTLs with different cell surface molecules play an important role in EBV infection .
