DNA methylation in cervical carcinogenisis,diagosis and treatment
10.3760/cma.j.issn.1673-422X.2010.01.022
- VernacularTitle:DNA甲基化与宫颈癌的发生及诊治
- Author:
Wenjie ZENG
;
Feng YE
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
DNA methylation
- From:
Journal of International Oncology
2010;37(1):69-72
- CountryChina
- Language:Chinese
-
Abstract:
DNA methylation is a common process of epigenetics,and also is the third mechanism of tumor related gene inactivation.It plays an important role in the development of cervical cancer.Studies show that methylation of p16,FHIT,IGSF and DAPK1 have relationship with cervical cancer,thus they may be a biomarker for the early diagnosis of cervical cancer.Meanwhile,advanced study of cervical cancer related gene methylation provides a new target point for treatment.
