Progress of the antiepileptic mechanisms of ketogenic diet
10.3760/cma.j.issn.1673-4408.2010.02.027
- VernacularTitle:生酮饮食抗癫(疒间)机制的研究进展
- Author:
Xinna JI
;
Jiong QIN
- Publication Type:Journal Article
- Keywords:
Ketogenic diet;
Epilepsy;
Iron channel;
Neurotransmitter
- From:
International Journal of Pediatrics
2010;37(2):193-196
- CountryChina
- Language:Chinese
-
Abstract:
Ketogenic diet (KD) is a high-fat,low-protein,low-carbohydrate diet that results in series of adaptive changes such as ketosis,fatty acid increasing and glycolysis depression.The mechanisms of the epilepsy correlated with the iron channel,neurotransmitter and neurocyte injury.The novel stresses the antiepileptic effects of above general changes in controlling the iron channels open or close,balancing the excitable and inhibitive neurotransmitters,increasing energy reserve,inhibiting free radical production and promoting neurocyte regeneration.