Progress in treatment of asthma with immunomodulator
10.3760/cma.j.issn.1673-4408.2010.02.028
- VernacularTitle:免疫调节剂在哮喘治疗中的研究进展
- Author:
Hongmei LI
;
Qingnan HE
- Publication Type:Journal Article
- Keywords:
Asthma;
Immunomodulator;
Treatment
- From:
International Journal of Pediatrics
2010;37(2):197-199
- CountryChina
- Language:Chinese
-
Abstract:
As we know more and more about asthma pathogenesis and chronic inflammatory disorder mechanism,and additional immunomodulator options become available.Studies have suggested that Th2 cell differentiation increases,and Th1 cell differentiation reduces in asthma.Therefore,it becomes an important immunotherapy method to modulate the Th1/Th2 response by promoting Th1 cytokines and inhibiting Th2 cytokines.At present,the use of immunomodulator such as anti-IgE antibody,anti-IL-5 agents,CpG oligodeoxynucleotides,imiquimod,bacterial extracts,Chinese medicine in asthma has already made some progress,and besidse it demonstrate great efficacy in clinical.
