Effect of Buyanghuanwu decoction pretreatment on heart function of MIRI rabbits

VernacularTitle:补阳还五汤预处理对MIRI兔心功能的影响
Author: Shuzhen LI ; Xiaoyu WANG ; Yanmei YANG ; Yu GU ; Lanlan ZHANG
Publication Type:Journal Article
Keywords: Buyang huanwu decoction/PD; Myocardial ischemia/DT; Reperfusion injury/DT; Heart/DE
From: Journal of Chinese Physician 2010;12(2):191-193
CountryChina
Language:Chinese
Abstract: Objective To explore the protective mechanisms of Buyanghuanwu decoction (BHD) on heart function by observing its effect on MIRI rabbits. Methods The rabbits were randomly divided into three groups, including sham group, model group, and BHD group. After pretreatment for one week, the model of myocardial ischemia reperfusion injury was established by ligating the branch of left coronary arter-y. The changes of electrocardiography were observed, and the values of LVSP, + dp/dtmax, - dp/dtmax were recorded and compared. Results Compared with the model group, the values of LVSP, + dp/dtmax, - dp/dtmax in BHD group were significantly increased (P<0.01 ). Conclusion BHD can improve heart function of MIRI rabbits.