Relationship of vascular endothelial function and atherosclerosis in elderly patients with coronary artery disease
10.3760/cma.j.issn.0254-9026.2010.03.010
- VernacularTitle:老年冠心病患者血管内皮功能与动脉粥样硬化的关系
- Author:
Chenghuan ZHENG
;
Lin WANG
;
Changyu ZHOU
;
Guangping LI
;
Lixiu YANG
;
Xin CHEN
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Endothelium,vascular;
Arteriosclerosis
- From:
Chinese Journal of Geriatrics
2010;29(3):212-214
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the endothelial function and atherosclerosis in patients with coronary artery disease (CAD).Methods Two-dimensional echocardiography (2-DE) was used tomeasure changes in brachial artery inner diameter as parameter of endothelium-dependant and endothelium-nondependant vascular diastolic function and pathologic characters of carotid atherosclerosis in 90 elderly CAD patients and 30 controls.Results Endothelium-dependant vascular diastolic function and endothelium-non dependant diastolic function were significantly decreased in CAD group as compared with control group [(9.08±2.28)% and (6.14±2.21)% vs.(15.58±2.20)%, P<0.01].The carotid intima-media thickness and plaque score were significantly increased in CAD group as compared with control group.Conclusions There are correlations of endothelium dysfunction and carotid atherosclerosis are relatied to with coronary atherosclerosis.
