Progress of cardiac stem cell transplantation
10.3760/cma.j.issn.1673-4408.2010.02.018
- VernacularTitle:干细胞心肌移植的研究进展
- Author:
Li WEI
;
Xingyuan HUANG
- Publication Type:Journal Article
- Keywords:
Stem cell;
Transplantation;
Myocardial infarction;
Cardiomyopathy
- From:
International Journal of Pediatrics
2010;37(2):164-167
- CountryChina
- Language:Chinese
-
Abstract:
Cardiomyopathy is a serious disease for children's health.With the development of medical methods,cardiac stem cell transplantation has brought hopes for treatment of cardiovascular diseases,it has also become a research hotspot in recent years.Several different types of cells have been used in cardiac stem cell transplantation currently,including embryonic stem cells,bone marrow derived stem cells,skeletal myoblasts,umbilical cord blood stem cells,adipose stem cells,etc.The delivery is including intramyocardial injection,intracoronary injection,intravenous injection,and tissue-engineered constructs.The adverse reactions are ventricular arrhythmias,oncogenic transformation,multiorgan seeding,unintended cell differentiation,accelerated atherogenesis and coronary thrombosis.