Relationship between STAT3 and tumor
10.3760/cma.j.issn.1673-422X.2010.01.006
- VernacularTitle:STAT3与肿瘤的关系
- Author:
Na WANG
- Publication Type:Journal Article
- Keywords:
Signal transducer and activator of transcription 3;
Gene;
Neoplasms
- From:
Journal of International Oncology
2010;37(1):18-20
- CountryChina
- Language:Chinese
-
Abstract:
At present,research of genes and signal transduction pathway for etiology and pathogenesy of diseases is a hot topic.STAT3 signal transduction plays an important role in regulating cell proliferation,differentiation,survival and apoptosis.As a point of convergence for numerous oneogenie signaling pathways,STAT3 is constitutively activated in diverse human cancer cells.Current study suggest that activation of STAT3 signal transduction is closely related to the currence,development and malignant biological behaviors of tumor.STAT3 has been identified as a promising target for cancer treatment.
